Slight health networkMessage: Why do some people how to eat not fat and some people even drink water will be fat? Child birth Why Caesarean immunity? – All theses.
Why do some people with a drug to eat very effective, some people eat to no avail, and even side effects? Why do some people how to eat are not fat, and some people even drink water will be fat? Why everyone has cancer cells, but some people get cancer, some people may not cancer …
All this and genes. Dean of the College of Life Science, Zhejiang University, Min Xin, said: “all living things come from genetics, genetics in fact is the United States speak of futuremedicine of the future of medicine in the future (life science) told us directly related to genetics. Recently held the first Global Chinese Congress of Genetics, more than 400 Chinese geneticists from home and abroad gathered in a 74 well-known experts at the meeting to share a special report in the form of the most cutting-edge research.
Obesity in the end to where the gene
“Genes are relatively constant, but also mutates. Huanming academician, director of the China Council for International Cooperation Genetics, the gene is like a ghost. Like someone said, some people how to eat are not fat, and some people even drink water also fat, which is each person's genetic result of the different.
Our research group recently published a result of a bacterial directory, published almost more than 2000 kinds of bacteria, intestinal distribution of the average each person has about 170 kinds. We found that obesity is largely genetically determined. Huanming said.
In the end where the gene related to it? “We use the intestinal microbial gene made the mice obese experiment. Screening two rats, feeding practices, food intake, one fat, one thin. How to give a fat rats lose weight? Do not move to micro-organisms in its intestines for a change, so that the fat is now thinner, another upside down. Huanming said.
Although this study is still at an experimental stage, for clinical, and believe the gospel of obese patients.
Why child birth than caesarean sections immunity
Whether the person will get the disease, not a single determined by their genes, but also the genes of various bacteria of the body. Because the human body in the course of the operation, the body of a variety of bacteria, fungi involved in innate good or bad, this bacteria has also decided to human health.
Huanming academicians from this point of view, he believes that children than natural labor Caesarean section a child's body immunity. This is because the newborn in the delivery of the natural mouth sucked into the micro-organisms is the large number of probiotics in the mother's birth canal. Carrying the genes for these probiotics, they set up camp in the digestive tract of the infant sterile, then the formation of a variety of flora, makes the body maintain a healthy balance. Obviously, the children of caesarean sections is precisely had lost this opportunity, so that they “lose” in the starting line of the immunity. Of course, these studies only just begun.
AIDSWhat is the toxic gene weakness
While everyone has cancer cells, but some people have suffered from cancer, and some people not cancerous, this is because the gene. The impact of genes on cancer is also a focus of this meeting of experts of common concern. Genetic research on AIDS has also been a new breakthrough. National “1000 Plan” Distinguished Professor, Zhejiang University, College of Life Science, Professor Shen Binghui found in the study, “venomous” of the AIDS virus and human genes combine, people can no longer get rid of it . Do not let people's genetic integration is expected to prevent HIV.
Chenbing Hui said: “Our team has recently obtained a patent, is the use of the HIV genome, developed a new drug of the treatment of HIV-susceptible populations. “
Twenty or thirty years ago, scientists have to figure out the HIV genome, but it is not clear that the HIV genome sequences, RNA (ribonucleic acid) into double-stranded structure of DNA (deoxyribonucleic acid), the middle a three-chain structure, many people do not know what function. “I think this is an intermediate, it must be repaired in order to become a normal HIV genome. Now, we find the three-chain structure restored to two-chain structure of small molecules. Blocking the repair of the three-chain structure, has become our treatment of HIV has a sense of the crowd of new ideas. Chenbing Hui said.
Professor Shen Binghui intervention of HIV drugs block the gene repair process, has entered a clinical one. In this way, in the treatment of HIV infection stage. If you can make better progress in the further clinical, this method will bring the gospel of HIV-infected population.
Whether the addiction of tobacco and alcohol also depends on the gene
“If you carry a gene, then you go to 1 bar, it may be drunken; If you do not have this gene, even every day, socializing drink, and do not cause addiction. “State” Thousand Talents Program “Distinguished Professor, School of Zhejiang Medical Genomics and Bioinformatics Research Center Director Professor Li Mingding said,” years of molecular biology, especially zoology experiments show that there part of the candidate gene for genetic variants and smoking addiction related. “
Li set in the United States to study the subject of smoking addiction for white and black Americans. “Now, we are doing genome-wide scan. More than 20,000 genes, humans probably only know 30% -40% of the role of genes to these genes have a more extensive understanding of need through the use of genome-wide scan, and new means for further study. For the corresponding genetic locus (loci: genetic markers on chromosome location) to find disease genes, based on existing drugs, to carry out individualized medical research: through the establishment of specific drugs and specific gene loci correspondence between use of specific drugs for specific populations, to avoid side effects, to further improve the efficacy and safety of disease prevention and treatment. “Li Ting said.
After years of research, Li given group has developed a-specific gene loci and alcohol drugs, has completed phase II clinical trials, and have achieved a significant effect.